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A Brief History of Magnetic Resonance at Nottingham

The University of Nottingham has long been at the centre of developments in Magnetic Resonance techniques. Much of the early, pioneering work on MRI was done here, by Peter (now Sir Peter) Mansfield in the mid-1970s. Before that, NMR was only able to provide information about a sample as a whole, rather than details about the internal structure of a sample, or for that matter, a person. One of the earliest important contributions that Sir Peter made to MRI was to invent the method whereby we can image a slice through a person.The early MRI pictures were generally coarse and slow to produce, whereas nowadays MRI images can be exquisite in their detail. This change has been brought about by a combination of massive improvement in scanner hardware and the development of more clever techniques. Nottingham has played and important role in improving the hardware.

However Nottingham is probably best known for the invention of EPI, which Peter Mansfield first proposed in the late 1970s, although it has only been used in medical imaging since the early 1990s. It is now used widely to look at brain function.

Sir Peter Mansfield shared the Nobel Prize for his part in the development of MRI in 2003.

 

Peter Mansfield's Key Contributions to the Development of MRI

1973: Independent invention of MRI
NMR diffraction in solids?
Mansfield and Grannell
J. Phys. C: Solid State Phys., 6, L422, 1973.
1974: Slice selection
Garroway and Grannell
J. Phys. C, 7, L457, 1974.
1977: Echo-planar imaging
Multiplanar image formation using NMR
Mansfield
J. Phys. C., 10, L55-58, 1977.
1986: Shielded gradients
Active Magnetic screening of gradient coils in NMR imaging
Mansfield and Chapman
J. Magn. Reson., 66, 573, 1986.
 

 

In the mid 1970s there were three groups in the then Department of Physics at the University of Nottingham, all working on NMR and subsequently MRI. The competition between them was fierce, but highly productive. Famous names from the early 1970s include Raymond Andrew, Peter Mansfield, Peter Alan and Bill Derbyshire. Waldo Hinshaw produced this image of a spring onion (selected to give the best filling factor in the small diameter sample tube) in 1974. Prof Andrew made a collage from the raw data and the picture was exhibited in University's central Portland Building for a time.

 



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